SCHEMBL1621090

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1620026	0.92	ALDH1A1 (0.42)	ALDH1A1KDM4ETDP1LMNAHPGD
	SCHEMBL10289183	0.86	CYP3A4 (0.34)	ALDH1A1KDM4ETDP1MEN1KMT2A
	SCHEMBL1618900	0.84	ALDH1A1 (0.43)	ALDH1A1KDM4ETDP1LMNAHPGD
	SCHEMBL1620934	0.81	ALDH1A1 (0.46)	ALDH1A1KDM4ETDP1LMNAHPGD
	SCHEMBL13998946	0.81	HTR2A (0.35)	ALDH1A1KDM4ETDP1LMNAMAPT
	SCHEMBL22297245	0.78	LMNA (0.41)	ALDH1A1KDM4ETDP1LMNAHPGD
	SCHEMBL1620156	0.78	LMNA (0.43)	ALDH1A1KDM4ETDP1LMNAHPGD
	SCHEMBL13085643	0.76	POLB (0.36)	ALDH1A1MEN1KMT2APOLBGAA
	SCHEMBL10741703	0.76	ALDH1A1 (0.36)	ALDH1A1KDM4ETDP1LMNAHPGD
	SCHEMBL21752430	0.74	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.