Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | CTSS | P25774 | 3/20 | 0.46 |
| ▸ | CTSK | P43235 | 3/20 | 0.46 |
| ▸ | CTSH | P09668 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212659 | 0.94 | C5AR1 (0.54) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL30901130 | 0.91 | AGTR1 (0.49) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL29608024 | 0.89 | C5AR1 (0.57) | C5AR1MC4ROPRM1OPRK1CXCR4 | |
| SCHEMBL29608116 | 0.89 | C5AR1 (0.57) | C5AR1MC4ROPRM1OPRK1CXCR4 | |
| SCHEMBL30504860 | 0.89 | C5AR1 (0.52) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL29607839 | 0.89 | C5AR1 (0.56) | C5AR1MC4ROPRM1OPRK1CXCR4 | |
| SCHEMBL31409175 | 0.88 | C5AR1 (0.53) | C5AR1NTSR2NTSR1SORT1 | |
| SCHEMBL30901125 | 0.88 | AGTR2 (0.47) | C5AR1CTSLCTSSCTSKCTSH | |
| SCHEMBL30230017 | 0.88 | OPRM1 (0.58) | CTSLCTSSCTSKCTSHOPRM1 | |
| SCHEMBL30272476 | 0.88 | NTSR1 (0.46) | C5AR1MC4RNTSR2NTSR1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109806395-A | Medical usage | 瓦力雷克斯有限公司 | 2019-05-28 | — | — | CN | claimed |
| CN-104136082-B | medical use | 瓦力雷克斯有限公司 | 2019-03-08 | — | — | CN | claimed |
| EP-2773427-A2 | MEDICAL USE | Valirx Plc. (GB) | 2014-09-10 | — | — | EP | claimed |
| WO-2013064830-A2 | MEDICAL USE | VALIRX PLC (GB) | 2013-05-10 | — | — | WO | claimed |