Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16212740 | 0.85 | TLR9 (0.46) | — | |
| SCHEMBL6390141 | 0.84 | RAB9A (0.38) | KDM4ENPC1RAB9A | |
| SCHEMBL16212728 | 0.81 | SUV39H2 (0.40) | — | |
| SCHEMBL16212585 | 0.80 | SUV39H2 (0.37) | — | |
| SCHEMBL16212479 | 0.77 | SUV39H2 (0.41) | — | |
| SCHEMBL5308528 | 0.76 | RAB9A (0.45) | KDM4ENPC1RAB9A | |
| SCHEMBL2127673 | 0.72 | ALDH1A1 (0.46) | KDM4ENPC1RAB9A | |
| SCHEMBL4828410 | 0.67 | — | — | |
| SCHEMBL7238218 | 0.66 | MAPT (0.31) | NPC1RAB9A | |
| SCHEMBL3584562 | 0.65 | NUDT1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991983-A1 | 2-PHENYL OR 2-HETARYL IMIDAZOL[1,2-a]PYRIDINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177458-A1 | 2-PHENYL OR 2-HETARYL IMIDAZOL[1,2-a]PYRIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-06 | — | — | WO | disclosed |