Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213687 | 0.89 | KMT2A (0.39) | ALDH1A1KMT2AMEN1GAALMNA | |
| SCHEMBL24259735 | 0.87 | MEN1 (0.48) | ALDH1A1CNR1KMT2AMEN1GAA | |
| SCHEMBL14240967 | 0.83 | EPHX1 (0.36) | ALDH1A1KMT2AMEN1NAAA | |
| SCHEMBL28055110 | 0.77 | ALDH1A1 (0.31) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL14240966 | 0.76 | EPHX1 (0.46) | ALDH1A1KMT2AMEN1GAANAAA | |
| SCHEMBL16384812 | 0.76 | LMNA (0.46) | ALDH1A1CNR1KMT2AGAAHPGD | |
| SCHEMBL23006504 | 0.74 | MEN1 (0.53) | KMT2AMEN1GAAHTT | |
| SCHEMBL25969893 | 0.72 | HDAC1 (0.58) | ALDH1A1KMT2AMEN1GAAHPGD | |
| SCHEMBL16213675 | 0.70 | LMNA (0.30) | LMNA | |
| SCHEMBL25779371 | 0.70 | MEN1 (0.44) | ALDH1A1KMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236695-A1 | BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR | MONTELINO THERAPEUTICS, INC. (US) | 2021-11-25 | — | — | WO | disclosed |
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |