Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25536824 | 0.76 | GABRP (0.41) | — | |
| SCHEMBL16213696 | 0.76 | LMNA (0.38) | LMNA | |
| SCHEMBL13815320 | 0.76 | ALDH1A1 (0.40) | LMNA | |
| SCHEMBL22677513 | 0.75 | USP2 (0.31) | — | |
| SCHEMBL26292875 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL16213690 | 0.74 | L3MBTL1 (0.41) | — | |
| SCHEMBL24259735 | 0.72 | MEN1 (0.48) | — | |
| SCHEMBL24240932 | 0.71 | ALDH1A1 (0.41) | LMNA | |
| SCHEMBL16213677 | 0.70 | ALDH1A1 (0.37) | LMNA | |
| SCHEMBL12283218 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |