SCHEMBL16214907

SCHEMBL16214907

O=C(OCCC(F)(F)C(F)(F)[SH](=O)=O)C1CC2CCC1C2

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
HSD11B1 P28845 1/20 0.32
HPGD P15428 1/20 0.31
EPHX2 P34913 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16214824 0.92 POLB (0.35) POLBHSD11B1
SCHEMBL16214874 0.91 POLB (0.35) POLBHSD11B1
SCHEMBL16213954 0.84 POLB (0.39) POLBHSD11B1HPGDEPHX2L3MBTL1
SCHEMBL12039740 0.81 POLB (0.36) POLBHSD11B1HPGD
SCHEMBL16214828 0.80 ALDH1A1 (0.33) POLB
SCHEMBL16214881 0.80 TDP1 (0.39) POLBHPGDL3MBTL1
SCHEMBL16213970 0.76 POLB (0.37) POLBHSD11B1HPGDEPHX2L3MBTL1
SCHEMBL16213983 0.75 POLB (0.36) POLBHSD11B1HPGDEPHX2L3MBTL1
SCHEMBL13801380 0.75 POLB (0.38) POLBHSD11B1HPGDEPHX2L3MBTL1
SCHEMBL16214869 0.75 ADRB2 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877960-B2 Fluoroalkanesulfonic acid ammonium salts and method for producing same CENTRAL GLASS COMPANY, LIMITED (JP) 2014-11-04 US disclosed
US-20110313190-A1 Fluoroalkanesulfonic Acid Ammonium Salts and Method for Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2011-12-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313190-A1 Fluoroalkanesulfonic Acid Ammonium Salts and Method for Producing Same PFAS, ARSA, NOTUM POLB 644/4885HSD11B1 1955/4885HPGD 4221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.