Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24722768 | 0.77 | GAA (0.40) | GAA | |
| SCHEMBL12853939 | 0.70 | — | — | |
| SCHEMBL6509835 | 0.69 | GAA (0.31) | GAA | |
| SCHEMBL4257458 | 0.69 | GAA (0.39) | GAA | |
| SCHEMBL16215576 | 0.67 | PAOX (0.31) | — | |
| SCHEMBL2904493 | 0.67 | — | — | |
| Hydroxyamine SCHEMBL20338128 | 0.66 | TSHR (0.39) | — | |
| SCHEMBL5695058 | 0.65 | ALDH1A1 (0.39) | GAA | |
| SCHEMBL6222998 | 0.65 | GAA (0.41) | GAA | |
| SCHEMBL7981776 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588197-B1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2014-11-05 | — | — | EP | disclosed |