Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3799414 | 0.76 | TDP1 (0.30) | — | |
| SCHEMBL14836211 | 0.74 | GLRA1 (0.33) | — | |
| SCHEMBL27829714 | 0.73 | TDP1 (0.33) | — | |
| SCHEMBL28503473 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL1260015 | 0.72 | TSHR (0.34) | — | |
| SCHEMBL990593 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL3733898 | 0.70 | TDP1 (0.31) | — | |
| SCHEMBL29155241 | 0.70 | CTSD (0.31) | — | |
| SCHEMBL29155250 | 0.69 | TDP1 (0.36) | — | |
| SCHEMBL24722768 | 0.69 | GAA (0.40) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107543-A1 | Fluoro linkers and their use as linkers for enzyme-activated drug conjugates | PFIZER INC. | 2005-05-19 | — | — | US | claimed |
| WO-2001000240-A2 | ANTITUMOR COMPOUND | PHARMACIA & UPJOHN SPA (IT) | 2001-01-04 | — | — | WO | claimed |
| WO-2001000240-A2 | ANTITUMOR COMPOUND | PHARMACIA & UPJOHN SPA (IT) | 2001-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107543-A1 | Fluoro linkers and their use as linkers for enzyme-activated drug conjugates | CES2, CBR3, APEH | GAA 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.