Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237927 | 1.00 | CYP11B1 (0.34) | CYP11B1CYP11B2KDM1AABL1TRPV1 | |
| SCHEMBL10237901 | 0.91 | PDE3B (0.34) | ABL1SLC6A3 | |
| SCHEMBL16215997 | 0.90 | SLC6A3 (0.39) | ABL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10237915 | 0.90 | SLC6A3 (0.39) | ABL1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10237917 | 0.86 | DHODH (0.35) | PDE4BPDE4CPDE4DSLC6A3 | |
| SCHEMBL10237956 | 0.86 | CYP11B1 (0.36) | CYP11B1CYP11B2KDM1AABL1TRPV1 | |
| SCHEMBL10237906 | 0.86 | NOTUM (0.46) | PTGS2 | |
| SCHEMBL10238068 | 0.85 | PIK3CA (0.41) | KDM1APTGS2SLC6A3PTGS1 | |
| SCHEMBL10238063 | 0.84 | EIF4E (0.35) | KDM1APDE4A | |
| SCHEMBL10238020 | 0.83 | PTGS2 (0.41) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176222-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2014-11-05 | — | — | EP | disclosed |