Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | MAP3K14 | Q99558 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10237915 | 1.00 | SLC6A3 (0.39) | SLC6A3KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10237917 | 0.92 | DHODH (0.35) | SLC6A3KDM4EMAPTACHENPC1 | |
| SCHEMBL10237901 | 0.92 | PDE3B (0.34) | SLC6A3MAPTPDE3BPDE3AABL1 | |
| SCHEMBL16215977 | 0.90 | CYP11B1 (0.34) | SLC6A3ABL1PDE4APDE4BPDE4C | |
| SCHEMBL10237927 | 0.90 | CYP11B1 (0.34) | SLC6A3ABL1PDE4APDE4BPDE4C | |
| SCHEMBL10237906 | 0.87 | NOTUM (0.46) | KDM4EALDH1A1MAPTPDE3BPDE3A | |
| SCHEMBL10238063 | 0.87 | EIF4E (0.35) | KDM4EALDH1A1MAPTL3MBTL1PDE4A | |
| SCHEMBL10237934 | 0.86 | RAB9A (0.40) | SLC6A3KDM4EALDH1A1MAPTACHE | |
| SCHEMBL10237945 | 0.85 | SLC6A3 (0.37) | SLC6A3KDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL10238084 | 0.85 | S1PR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176222-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2014-11-05 | — | — | EP | disclosed |