Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608047 | 1.00 | HRH3 (0.41) | HRH3GAAPTGDR2ALDH1A1KDM4E | |
| SCHEMBL10237937 | 1.00 | HRH3 (0.41) | HRH3GAAPTGDR2ALDH1A1KDM4E | |
| SCHEMBL10238014 | 0.89 | GLA (0.36) | GAAPTGDR2ALDH1A1KDM4EMAPT | |
| SCHEMBL10237957 | 0.88 | PTGDR2 (0.37) | HRH3PTGDR2ALDH1A1KDM4EMAPT | |
| SCHEMBL10238117 | 0.88 | DCK (0.42) | PTGDR2KDM4EHPGDKMT2AMAPT | |
| SCHEMBL10238114 | 0.88 | L3MBTL1 (0.44) | HRH3GAAPTGDR2ALDH1A1KDM4E | |
| SCHEMBL10237945 | 0.87 | SLC6A3 (0.37) | ALDH1A1KDM4ECYP1A2HPGDCYP2C19 | |
| SCHEMBL10238159 | 0.87 | L3MBTL1 (0.32) | PTGDR2 | |
| SCHEMBL10238088 | 0.86 | DCK (0.32) | PTGDR2 | |
| SCHEMBL10237940 | 0.85 | PDE3B (0.34) | HRH3PTGDR2ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2176222-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2014-11-05 | — | — | EP | disclosed |