Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | TSHR | P16473 | 1/20 | 0.83 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.83 |
| ▸ | LMNA | P02545 | 4/20 | 0.76 |
| ▸ | RAB9A | P51151 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 8/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2016019 | 0.84 | LMNA (0.80) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL16217087 | 0.83 | LMNA (0.69) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL16217081 | 0.80 | TSHR (0.78) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL7681133 | 0.73 | BUB1 (0.69) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL2014406 | 0.73 | ALDH1A1 (0.74) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL10090689 | 0.71 | POLB (0.83) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL7685234 | 0.71 | ALOX15 (0.56) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL7683273 | 0.69 | ADORA2A (0.59) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL14758473 | 0.69 | SMN1; SMN2 (0.79) | ALOX15TSHRHSD17B10LMNARAB9A | |
| SCHEMBL7681249 | 0.69 | ALOX15 (0.53) | ALOX15TSHRHSD17B10LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329863-A1 | NOVEL ANTIPRION COMPOUNDS | PRNP, PSEN1, PSEN2 | ALOX15 1534/4885TSHR 4745/4885HSD17B10 2270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.