SCHEMBL16217664

SCHEMBL16217664

CC(COC(=O)c1ccc(C(=O)OC(C)COC(=O)C2CCCCC2)cc1)OC(=O)c1ccc(C(=O)OCC(C)OC(=O)C2CCCCC2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
SCN1A P35498 1/20 0.47
SCN2A Q99250 1/20 0.47
SCN3A Q9NY46 1/20 0.47
ALDH1A1 P00352 4/20 0.41
HTT P42858 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TSHR P16473 1/20 0.41
MDM2 Q00987 1/20 0.41
USP2 O75604 1/20 0.41
ALOX15 P16050 1/20 0.41
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL812854 0.88 LMNA (0.54) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL812974 0.85 ADRB2 (0.49) LMNAALDH1A1ADRB2ADRB1ADRB3
SCHEMBL13700327 0.78 ALDH1A1 (0.48) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL5021074 0.76 SCN1A (0.49) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL22579671 0.75 CYP4F2 (0.50) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL813138 0.75 ALDH1A1 (0.50) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL24055108 0.74 MAPT (0.49) LMNAALDH1A1ADRB2ADRB1ADRB3
SCHEMBL1784739 0.74 ADRB2 (0.59) ALDH1A1NPC1RAB9AADRB2ADRB1
SCHEMBL16217637 0.74 ALDH1A1 (0.61) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL12559135 0.74 ALDH1A1 (0.61) LMNACYP1A2CYP2D6SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9581861-B2 Phase difference film, polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2017-02-28 US disclosed
US-20140326930-A1 PHASE DIFFERENCE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2014-11-06 US disclosed