Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 8/20 | 0.36 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | HRH2 | P25021 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16221628 | 0.88 | PDE4B (0.43) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL16218323 | 0.79 | HTR2C (0.36) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL5210690 | 0.75 | ACMSD (0.47) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL2586831 | 0.72 | NPC1 (0.54) | KCNH2HRH3NPC1MAPTRAB9A | |
| SCHEMBL16222135 | 0.71 | ACMSD (0.35) | MAPTRAB9ABACE1 | |
| SCHEMBL16221631 | 0.68 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL16221932 | 0.68 | ACMSD (0.34) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL2586793 | 0.67 | HRH3 (0.44) | KCNH2HRH3NPC1MAPTRAB9A | |
| SCHEMBL19986350 | 0.67 | CYP3A4 (0.37) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL31267631 | 0.66 | HTR2C (0.42) | HTR2CADRA2ADRD2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140329177-A1 | CYCLIC COMPOUND, METHOD FOR PRODUCING SAME, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2014-11-06 | — | — | US | disclosed |