Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31267768 | 0.91 | CA12 (0.47) | NPC1MAPTRAB9AHRH3KCNH2 | |
| SCHEMBL603311 | 0.83 | HRH3 (0.51) | NPC1MAPTRAB9AHRH3KCNH2 | |
| SCHEMBL12835619 | 0.83 | ESR2 (0.47) | NPC1MAPTRAB9AHRH3POLB | |
| SCHEMBL603312 | 0.83 | HRH3 (0.51) | NPC1MAPTRAB9AHRH3KCNH2 | |
| SCHEMBL23084958 | 0.80 | NPC1 (0.41) | NPC1MAPTRAB9AHRH3KCNH2 | |
| SCHEMBL61119 | 0.80 | HRH3 (0.55) | NPC1MAPTRAB9AHRH3KCNH2 | |
| SCHEMBL15869166 | 0.80 | ALDH1A1 (0.42) | NPC1MAPTRAB9AMEN1KMT2A | |
| SCHEMBL677295 | 0.79 | HRH3 (0.55) | NPC1RAB9AHRH3KCNH2MEN1 | |
| SCHEMBL10619463 | 0.79 | CYP2C9 (0.49) | NPC1MAPTRAB9AHRH3MEN1 | |
| SCHEMBL10619470 | 0.79 | CYP2C9 (0.49) | NPC1MAPTRAB9AHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769542-A | Sulfonamide orexin receptor agonists and uses thereof | 爵士制药爱尔兰有限公司 | 2024-03-26 | — | — | CN | disclosed |
| US-8765310-B2 | Nonaqueous electrolytic solution and nonaqueous electrolyte secondary battery using the same | HITACHI, LTD. (JP) | 2014-07-01 | — | — | US | disclosed |
| CN-102237552-B | Nonaqueous electrolytic solution and nonaqueous electrolyte secondary battery using the same | HITACHI LTD | 2014-05-28 | — | — | CN | disclosed |
| CN-102237552-A | Nonaqueous electrolytic solution and nonaqueous electrolyte secondary battery using the same | HITACHI LTD | 2011-11-09 | — | — | CN | disclosed |
| US-20110269026-A1 | NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME | HITACHI, LTD. (JP) | 2011-11-03 | — | — | US | disclosed |