Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2151852 | 0.93 | ALDH1A1 (0.41) | ALDH1A1MAPK1TDP1TSHR | |
| SCHEMBL3519677 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL21925348 | 0.83 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1TSHR | |
| SCHEMBL3133315 | 0.83 | ALDH1A1 (0.35) | ALDH1A1MAPK1TDP1TSHR | |
| SCHEMBL7119977 | 0.83 | ALDH1A1 (0.33) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL17715106 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPK1TDP1TSHR | |
| SCHEMBL271230 | 0.71 | — | — | |
| SCHEMBL2151814 | 0.71 | — | — | |
| SCHEMBL16218410 | 0.69 | ALDH1A1 (0.32) | ALDH1A1MAPK1TDP1 | |
| SCHEMBL6907056 | 0.69 | ALDH1A1 (0.37) | ALDH1A1MAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9327034-B2 | Branched polyethylene glycol and use thereof | UNIVERSITY OF TSUKUBA, A JAPANESE NATIONAL UNIVERSITY (JP) | 2016-05-03 | — | — | US | disclosed |
| US-20140329290-A1 | NOVEL BRANCHED POLYETHYLENE GLYCOL AND USE THEREOF | UNIVERSITY OF TSUKUBA, A JAPANESE NATIONAL UNIVERSITY (JP) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329290-A1 | NOVEL BRANCHED POLYETHYLENE GLYCOL AND USE THEREOF | FGF2, HDGF, HSD17B14 | ALDH1A1 340/4885MAPK1 2674/4885TDP1 4476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.