Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 6/20 | 0.57 |
| ▸ | DUSP3 | P51452 | 6/20 | 0.57 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 3/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4575369 | 0.82 | PTPN7 (0.54) | PTPN7DUSP3RPS6KB1P2RX7NR3C2 | |
| SCHEMBL17198804 | 0.82 | TRPV1 (0.43) | RPS6KB1P2RX7 | |
| Hydrochloric Acid SCHEMBL28128875 | 0.80 | TRPV1 (0.42) | RPS6KB1 | |
| Hydrochloric Acid SCHEMBL30496710 | 0.80 | TRPV1 (0.42) | RPS6KB1 | |
| SCHEMBL30496726 | 0.80 | ALDH1A1 (0.52) | PTPN7DUSP3CTSD | |
| SCHEMBL17198950 | 0.80 | ALDH1A1 (0.52) | PTPN7DUSP3CTSD | |
| Hydrochloric Acid SCHEMBL28480591 | 0.79 | ALDH1A1 (0.51) | PTPN7DUSP3CTSD | |
| SCHEMBL17689391 | 0.78 | PTPN7 (0.57) | PTPN7DUSP3RPS6KB1P2RX7NR3C2 | |
| SCHEMBL15682779 | 0.78 | PTPN7 (0.53) | PTPN7DUSP3RPS6KB1P2RX7NR3C2 | |
| SCHEMBL14137984 | 0.78 | MLLT1 (0.35) | PTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200397927-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2020-12-24 | — | — | US | disclosed |
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-9550000-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-01-24 | — | — | US | disclosed |
| US-20140328756-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | PTPN7 4395/4885DUSP3 3535/4885RPS6KB1 4445/4885 |
| US-20140328756-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | PTPN7 4395/4885DUSP3 3535/4885RPS6KB1 4445/4885 |
| US-20200397927-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | PTPN7 4395/4885DUSP3 3535/4885RPS6KB1 4445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.