SCHEMBL1622

SCHEMBL1622

Fc1ccc(Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7026005 1.00
Fluoride SCHEMBL25376004 0.96 CYP2A6 (0.57)
SCHEMBL164941 0.96
SCHEMBL4600807 0.96
SCHEMBL1991704 0.90 MAPK1 (0.55)
SCHEMBL12562840 0.90 MAPK1 (0.55)
SCHEMBL9457196 0.90 MAPK1 (0.55)
SCHEMBL787631 0.90 MAPK1 (0.55)
Boric Acid SCHEMBL2466771 0.87 SMN1; SMN2 (0.52)
Bromobenzene SCHEMBL9228499 0.87 ALDH1A1 (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7195 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059814-A Preparation method of 1- (1, 1-dimethylpropoxy) -4-vinylbenzene 西安爱德克美新材料有限公司 2026-05-19 CN claimed
EP-4724442-A1 AGONISM-ANTAGONISM IN ENDOSOMAL TLRS BY MODULATING CHEMICAL FEATURES IN 8-OXOPURINE: PROCESS FOR PREPARATION AND APPLICATION THEREOF Council of Scientific and Industrial Research (IN) 2026-04-15 EP claimed
US-20250326756-A1 METHOD FOR PRODUCING 3,6-DISUBSTITUTED-IMIDAZO[1,2-B]PYRIDAZINE COMPOUNDS NUVATION BIO INC (US) 2025-10-23 US claimed
US-20250309354-A1 ELECTROLYTE COMPRISING AROMATIC COMPOUND WITH NON-FLUORINE HALOGEN SUBSTITUTE AND BATTERIES COMPRISING SAME FACTORIAL INC. 2025-10-02 US claimed
CN-119823008-A Preparation method of 4-methylsulfonyl phenylacetic acid 浙江东亚药业股份有限公司 2025-04-15 CN claimed
EP-4526306-A1 METHOD FOR PRODUCING 3,6-DISUBSTITUTED-IMIDAZO[1,2-B]PYRIDAZINE COMPOUNDS Anheart Therapeutics (Hangzhou) Co., Ltd. (CN) 2025-03-26 EP claimed
CN-114252515-B Method for separating and detecting related substances in p-bromofluorobenzene 广东东阳光药业股份有限公司 2025-03-14 CN claimed
CN-119591501-A Synthesis method of fluorine-containing biphenyl compound by one-pot method 江苏广域化学有限公司 2025-03-11 CN claimed
CN-119569640-A Preparation method of parol racemate 安徽英特美科技有限公司 2025-03-07 CN claimed
CN-119546609-A Process for preparing 3, 6-disubstituted-imidazo [1,2-b ] pyridazine compounds 葆元生物医药科技(杭州)有限公司 2025-02-28 CN claimed
EP-0455545-A1 Process for the preparation of mono- or polyalkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1991-11-06 EP claimed
EP-0434517-A2 Process for the preparation of mono- or poly-alkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1991-06-26 EP claimed
EP-0434516-A2 Process for the preparation of mono- or poly-alkoxylated aromatic compounds RHONE-POULENC CHIMIE (FR) 1991-06-26 EP claimed
EP-0405389-A1 Process for producing an aromatic compound Mitsubishi Chemical Corporation (JP) 1991-01-02 EP claimed
US-4956507-A GRIGNARD REAGENTS FROM P-HALOFLUOROBENZENE AND MAGNESIUM COUPLING TO FORM P,P*-DIFLUOROBIPHENYL PHILLIPS PETROLEUM COMPANY (US) 1990-09-11 US claimed
CN-1007839-B Compositions of liquid ion exchangers for use as acetylcholinergic ion-selective microelectrodes UNIV ZHEJIANG (CN) 1990-05-02 CN claimed
CN-1030480-A The preparation technology of liquid ion-exchanger composite used as acetylcholine ion-selective microelectrode UNIV ZHEJIANG (CN) 1989-01-18 CN claimed
EP-0173201-A1 Process for preparing aromatic bromo compounds HOECHST AKTIENGESELLSCHAFT (DE) 1986-03-05 EP claimed
US-4446075-A DIRECT BROMINATION RIEDEL-DE HAEN AG (DE) 1984-05-01 US claimed
EP-0034741-B1 PROCESS FOR THE PREPARATION OF A SUBSTITUTED BROMOFLUOROBENZENE AND 3-BROMO-4-FLUOROBENZONITRILE RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1983-12-21 EP claimed