Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PKLR | P30613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630070 | 0.87 | CYP3A4 (0.52) | GABRA1GABRB2CYP3A4CES2CES1 | |
| SCHEMBL30625397 | 0.87 | CYP3A4 (0.52) | GABRA1GABRB2CYP3A4CES2CES1 | |
| SCHEMBL29648809 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4MAPK1TDP1 | |
| SCHEMBL4882890 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4CES2CES1 | |
| SCHEMBL1950281 | 0.85 | GABRA1 (0.47) | GABRA1GABRB2CYP3A4MAPK1TDP1 | |
| SCHEMBL3626012 | 0.85 | GABRA1 (0.42) | GABRA1GABRB2CYP3A4CES2CES1 | |
| SCHEMBL158739 | 0.82 | GABRA1 (0.40) | GABRA1GABRB2CYP3A4CES1PARP1 | |
| SCHEMBL10614854 | 0.82 | GABRA1 (0.75) | GABRA1GABRB2CYP3A4ALDH1A1 | |
| SCHEMBL8590726 | 0.82 | CYP3A4 (0.39) | GABRA1GABRB2CYP3A4CES2CES1 | |
| SCHEMBL694840 | 0.80 | GABRA1 (0.39) | GABRA1GABRB2CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912405-A | Fluothidiazuron derivative and preparation method thereof | 河南省科学院高新技术研究中心 | 2025-05-02 | — | — | CN | claimed |
| CN-119431706-A | Fatigue-resistant polyurethane elastomer and preparation method and application thereof | 万勋科技(深圳)有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-104876859-B | Pyrrole worm is grand and preparation method thereof | 常州佳灵药业有限公司 | 2018-03-13 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| CN-117886824-B | 2, 3-Dihydropyrimido [4,5-d ] pyrimidine-4 (1H) -ketone derivative, preparation method and application thereof | 四川大学华西医院 | 2026-05-15 | — | — | CN | disclosed |
| EP-4713378-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2026-03-25 | — | — | EP | disclosed |
| US-20250223263-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NodThera Limited (GB) | 2025-07-10 | — | — | US | disclosed |
| EP-3500257-B1 | KINASE INHIBITOR COMPOUNDS, COMPOSITIONS, AND METHODS OF TREATING CANCER | ICAHN SCHOOL MED MOUNT SINAI (US) | 2025-07-02 | — | — | EP | disclosed |
| CN-119912405-A | Fluothidiazuron derivative and preparation method thereof | 河南省科学院高新技术研究中心 | 2025-05-02 | — | — | CN | disclosed |
| CN-119908364-A | Cotton defoliant containing fluhiuron derivative and application thereof | 河南省科学院高新技术研究中心 | 2025-05-02 | — | — | CN | disclosed |
| US-12247011-B2 | Selective inhibitors of NLRP3 inflammasome | NodThera Limited (GB) | 2025-03-11 | — | — | US | disclosed |
| CN-119431706-A | Fatigue-resistant polyurethane elastomer and preparation method and application thereof | 万勋科技(深圳)有限公司 | 2025-02-14 | — | — | CN | disclosed |
| EP-0683157-A1 | Sulfonylaminocarbonyltriazolinones as herbicides | BAYER AG (DE) | 1995-11-22 | — | — | EP | disclosed |
| US-5380863-A | Herbicidal sulphonylaminocarbonyltriazolinones having substituents which are bonded via sulphur | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| EP-0431291-A2 | Sulfonylaminocarbony-triazolinones having substituents attached through sulfur | BAYER AG (DE) | 1991-06-12 | — | — | EP | disclosed |
| EP-0422469-A2 | Sulfonylaminocarbonyltriazolinones | BAYER AG (DE) | 1991-04-17 | — | — | EP | disclosed |
| EP-0290392-A1 | N-Benzoyl-N'-trihalogen-haloalkoxyphenylureas, their preparation and their use in pest control | CIBA-GEIGY AG (CH) | 1988-11-09 | — | — | EP | disclosed |
| EP-0275558-A1 | Perfluoroalkenyloxybenzoic acid derivative, process for preparing the same and prepolymer of the derivative | DAIKIN INDUSTRIES, LIMITED (JP) | 1988-07-27 | — | — | EP | disclosed |
| EP-0243790-A1 | N-phenyl(thio)ureas and their functional derivatives, processes for their production and their use as pesticides | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-04 | — | — | EP | disclosed |
| CN-87102802-A | N-phenyl (sulphur) urea and functional derivatives thereof prepare their method and they are as the purposes of sterilant | — | 1987-10-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12247011-B2 | Selective inhibitors of NLRP3 inflammasome | NLRP3, NOD1, NLRP1 | GABRA1 2922/4885GABRB2 2882/4885CYP3A4 2832/4885 |
| US-20250223263-A1 | SELECTIVE INHIBITORS OF NLRP3 INFLAMMASOME | NLRP3, NOD1, NLRP1 | GABRA1 2922/4885GABRB2 2882/4885CYP3A4 2832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.