Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583955 | 0.76 | KMT2A (0.54) | MEN1KMT2AAOC3KDM4ESMN1; SMN2 | |
| SCHEMBL4583951 | 0.76 | KMT2A (0.54) | MEN1KMT2AAOC3KDM4ESMN1; SMN2 | |
| SCHEMBL4595769 | 0.74 | AOC3 (0.49) | MEN1KMT2AAOC3SLC6A4KDM4E | |
| SCHEMBL1622181 | 0.72 | MEN1 (0.50) | MEN1KMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL15311235 | 0.69 | AOC3 (0.54) | MEN1KMT2AAOC3KDM4ESMN1; SMN2 | |
| SCHEMBL15311237 | 0.69 | AOC3 (0.54) | MEN1KMT2AAOC3KDM4ESMN1; SMN2 | |
| SCHEMBL15311236 | 0.69 | AOC3 (0.54) | MEN1KMT2AAOC3KDM4ESMN1; SMN2 | |
| SCHEMBL4585446 | 0.68 | MEN1 (0.57) | MEN1KMT2AAOC3KDM4E | |
| SCHEMBL4585449 | 0.68 | MEN1 (0.57) | MEN1KMT2AAOC3KDM4E | |
| SCHEMBL4585162 | 0.68 | MEN1 (0.50) | MEN1KMT2AKDM4EADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928264-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2011-04-19 | — | — | US | disclosed |