Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20147738 | 0.79 | MTOR (0.40) | MAP3K12 | |
| SCHEMBL16224484 | 0.76 | MAP3K12 (0.33) | MAP3K12 | |
| SCHEMBL17510255 | 0.73 | MAP3K12 (0.56) | MAP3K12 | |
| SCHEMBL16224512 | 0.72 | — | — | |
| SCHEMBL9893112 | 0.61 | HRH4 (0.38) | — | |
| SCHEMBL9893030 | 0.61 | DRD4 (0.43) | — | |
| SCHEMBL9893053 | 0.59 | SORD (0.37) | — | |
| SCHEMBL9893033 | 0.59 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL9893045 | 0.59 | SMN1; SMN2 (0.56) | — | |
| SCHEMBL9893158 | 0.59 | SMN1; SMN2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014177060-A1 | BIHETEROARYL COMPOUNDS AND USES THEREOF | F.HOFFMANN-LA ROCHE AG (CH) | 2014-11-06 | — | — | WO | disclosed |