Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 3/20 | 0.45 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9359772 | 0.98 | KCNH3 (0.45) | SOAT1SOAT2KCNH3ACHEABL1 | |
| SCHEMBL9363853 | 0.93 | PKM (0.43) | SOAT1SOAT2KCNH3PKM | |
| SCHEMBL15557010 | 0.86 | ABL1 (0.54) | KCNH3ABL1EPHX2CNR2 | |
| SCHEMBL1521870 | 0.85 | PKM (0.45) | PKM | |
| SCHEMBL17586139 | 0.85 | PLK1 (0.51) | ACHEABL1EPHX2 | |
| SCHEMBL11935646 | 0.84 | FERMT2 (0.42) | — | |
| SCHEMBL16583821 | 0.83 | NQO2 (0.44) | ABL1EPHX2 | |
| SCHEMBL31146773 | 0.83 | ABL1 (0.51) | KCNH3ACHEABL1CNR1CNR2 | |
| SCHEMBL31146819 | 0.83 | ABL1 (0.51) | KCNH3ACHEABL1CNR1CNR2 | |
| SCHEMBL2847441 | 0.82 | FERMT2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014179438-A2 | GLYCOLIPID INHIBITION USING IMINOSUGARS | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2014-11-06 | — | — | WO | disclosed |