Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224813 | 0.98 | SOAT1 (0.45) | KCNH3SOAT1SOAT2PKMCNR1 | |
| SCHEMBL9363853 | 0.95 | PKM (0.43) | KCNH3SOAT1SOAT2PKMSHMT2 | |
| SCHEMBL1521870 | 0.87 | PKM (0.45) | PKMSHMT2HTT | |
| SCHEMBL15557010 | 0.84 | ABL1 (0.54) | KCNH3CNR2ABL1HCAR3EPHX2 | |
| SCHEMBL2847441 | 0.84 | FERMT2 (0.43) | SHMT2HTT | |
| SCHEMBL3714949 | 0.83 | ALOX15 (0.49) | KCNH3CNR1CNR2ACHEABL1 | |
| SCHEMBL17586139 | 0.83 | PLK1 (0.51) | ACHEABL1EPHX2 | |
| SCHEMBL11935646 | 0.82 | FERMT2 (0.42) | SHMT2 | |
| SCHEMBL31146773 | 0.81 | ABL1 (0.51) | KCNH3CNR1CNR2ACHEABL1 | |
| SCHEMBL31146819 | 0.81 | ABL1 (0.51) | KCNH3CNR1CNR2ACHEABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318893-B1 | Titanocenes, their use and N-substituted fluoroanilines | CIBA GEIGY AG (CH) | 1994-01-19 | — | — | EP | disclosed |
| US-5026625-A | Photoinitiators for polymerization of ethylenically unsaturated compounds | CIBA-GEIGY CORPORATION (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0318893-A2 | Titanocenes, their use and N-substituted fluoroanilines | CIBA-GEIGY AG (CH) | 1989-06-07 | — | — | EP | disclosed |