Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.51 |
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.51 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226652 | 1.00 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3GRIN2BADRA2A | |
| SCHEMBL16226921 | 0.84 | PRMT3 (0.52) | SLC6A2SLC6A4SLC6A3GRIN2BADRA2A | |
| SCHEMBL16225797 | 0.84 | PRMT3 (0.52) | SLC6A2SLC6A4SLC6A3GRIN2BADRA2A | |
| SCHEMBL5759913 | 0.80 | PRMT3 (0.56) | SLC6A2SLC6A4SLC6A3GRIN2BADRA2A | |
| SCHEMBL16226491 | 0.78 | KDM4E (0.58) | SLC6A3SIGMAR1RAB9ATSHRMEN1 | |
| SCHEMBL16226668 | 0.78 | KDM4E (0.58) | SLC6A3SIGMAR1RAB9ATSHRMEN1 | |
| Hydrochloric Acid SCHEMBL5756735 | 0.78 | PRMT3 (0.55) | SLC6A2SLC6A4SLC6A3GRIN2BADRA2A | |
| Hydrochloric Acid SCHEMBL28772274 | 0.78 | OPRM1 (0.48) | SLC6A2SLC6A4SLC6A3GRIN2BADRA2A | |
| SCHEMBL3471054 | 0.75 | RPS6KB1 (0.51) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL21752110 | 0.74 | TP53 (0.63) | SLC6A2SLC6A4SLC6A3GRIN2BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | SLC6A2 3677/4885SLC6A4 4285/4885SLC6A3 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.