Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 10/20 | 0.51 |
| ▸ | AKT1S1 | Q96B36 | 3/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473785 | 0.84 | MC4R (0.52) | RPS6KB1AKT1S1 | |
| SCHEMBL15719671 | 0.84 | SLC6A4 (0.58) | RPS6KB1AKT1S1CYP2D6 | |
| SCHEMBL3470901 | 0.84 | ACHE (0.53) | RPS6KB1AKT1S1ACHETSHR | |
| Hydrochloric Acid SCHEMBL17107316 | 0.83 | SLC6A4 (0.57) | RPS6KB1AKT1S1CYP2D6 | |
| SCHEMBL16460909 | 0.83 | P2RX7 (0.48) | RPS6KB1AKT1S1AKT1AKT2AKT3 | |
| SCHEMBL16461973 | 0.81 | RPS6KB1 (0.50) | RPS6KB1AKT1S1TP53LMNATHRB | |
| SCHEMBL14435697 | 0.81 | TP53 (0.48) | ACHETP53LMNATHRBCYP1A2 | |
| SCHEMBL468998 | 0.81 | CYP1A2 (0.62) | RPS6KB1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15017817 | 0.81 | CYP1A2 (0.62) | RPS6KB1LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5096867 | 0.81 | RPS6KB1 (0.52) | RPS6KB1CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105663-A1 | 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS | BAYER HEALTHCARE AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105663-A1 | 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS | F2, TFPI, PLAT | RPS6KB1 2981/4885AKT1S1 3067/4885ACHE 1054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.