Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.52 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 3/20 | 0.51 |
| ▸ | BCL2 | P10415 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23199059 | 0.95 | ALDH1A1 (0.61) | MAOAMAPTALDH1A1TSHRTDP1 | |
| SCHEMBL16227182 | 0.87 | BCL2 (0.67) | MAOAMAPTALDH1A1TDP1MAPK1 | |
| SCHEMBL30407933 | 0.87 | BCL2 (0.67) | MAOAMAPTALDH1A1TDP1MAPK1 | |
| SCHEMBL3182318 | 0.82 | BCL2 (0.73) | MAOAMAPTALDH1A1TSHRTDP1 | |
| SCHEMBL16226525 | 0.81 | ALDH1A1 (0.80) | MAOAMAPTALDH1A1TSHRTDP1 | |
| SCHEMBL28690510 | 0.78 | MAOA (0.63) | MAOAMAPTALDH1A1TSHRTDP1 | |
| Anthrarufin SCHEMBL187843 | 0.77 | MAOA (1.00) | MAOAMAPTALDH1A1TSHRTDP1 | |
| Anthrarufin SCHEMBL29363946 | 0.77 | MAOA (1.00) | MAOAMAPTALDH1A1TSHRTDP1 | |
| Anthrarufin SCHEMBL29874705 | 0.77 | MAOA (1.00) | MAOAMAPTALDH1A1TSHRTDP1 | |
| SCHEMBL3181589 | 0.76 | MAOA (0.79) | MAOAMAPTALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | MAOA 1208/4885MAPT 3619/4885ALDH1A1 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.