Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | LCK | P06239 | 1/20 | 0.80 |
| ▸ | GLA | P06280 | 1/20 | 0.80 |
| ▸ | THRB | P10828 | 1/20 | 0.80 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.80 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.80 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SLC37A4 | O43826 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Damnacanthal SCHEMBL29356591 | 0.89 | MAPT (1.00) | ALDH1A1MAPTLCKGLATHRB | |
| Damnacanthal SCHEMBL147246 | 0.89 | MAPT (1.00) | ALDH1A1MAPTLCKGLATHRB | |
| SCHEMBL16226906 | 0.81 | MAOA (0.59) | ALDH1A1MAPTLCKGLATHRB | |
| SCHEMBL19462002 | 0.79 | MAOA (0.66) | ALDH1A1MAPTLCKGLATHRB | |
| Juzunol SCHEMBL16226815 | 0.78 | MAOA (0.51) | ALDH1A1MAPTLCKGLATHRB | |
| SCHEMBL23199059 | 0.77 | ALDH1A1 (0.61) | ALDH1A1MAPTLCKGLATHRB | |
| SCHEMBL19462005 | 0.75 | MAOA (0.67) | ALDH1A1MAPTTHRBMAOAMEN1 | |
| SCHEMBL3257870 | 0.75 | EPHX2 (0.62) | ALDH1A1MAPTLCKGLATHRB | |
| SCHEMBL16226078 | 0.74 | MAOA (0.46) | ALDH1A1MAPTLCKGLATHRB | |
| SCHEMBL22394347 | 0.74 | PIM1 (0.63) | ALDH1A1MAPTTHRBMAOAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | ALDH1A1 1004/4885MAPT 3619/4885LCK 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.