SCHEMBL16229102

SCHEMBL16229102

COC(=O)CC1(C(=O)O)CC2CCC1C2

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.36
KARS1 Q15046 2/20 0.35
ALOX5AP P20292 4/20 0.33
EPHX2 P34913 3/20 0.32
CA12 O43570 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
TP53 P04637 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9572335 0.82 HSD11B1 (0.47) HSD11B1ALDH1A1
SCHEMBL11759010 0.82 HSD11B1 (0.47) HSD11B1ALDH1A1
SCHEMBL32688629 0.79 HSD11B1 (0.37) HSD11B1
SCHEMBL5930739 0.78 HSD11B1 (0.37) HSD11B1
SCHEMBL32689275 0.77 HSD11B1 (0.35) HSD11B1
SCHEMBL32688805 0.76 HSD11B1 (0.35) HSD11B1
SCHEMBL27564593 0.74 HSD11B1 (0.32) HSD11B1ALOX5APALDH1A1
SCHEMBL32688595 0.74 HSD11B1 (0.35) HSD11B1ALDH1A1
SCHEMBL32689077 0.74 HSD11B1 (0.35) HSD11B1EPHX2
SCHEMBL7861571 0.74 HSD11B1 (0.33) HSD11B1ALOX5APEPHX2CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9896537-B2 Norbornanyl rosin resin and process for preparing same YU HUI (US) 2018-02-20 US disclosed
US-9353213-B2 Functional norbornanyl ester derivatives, polymers and process for preparing same YU HUI (US) 2016-05-31 US disclosed
US-20160122469-A1 Functional norbornanyl ester derivatives, polymers and process for preparing same YU HUI (US) 2016-05-05 US disclosed
US-8883897-B2 Functional norbornanyl ester derivatives, polymers and process for preparing same New Functional Polymers LLC (US) 2014-11-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122469-A1 Functional norbornanyl ester derivatives, polymers and process for preparing same CYP1B1, DECR1, CAD HSD11B1 149/4885KARS1 888/4885ALOX5AP 131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.