Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15430483 | 1.00 | DEGS1 (0.50) | DEGS1SLC6A2SLC6A4ALDH1A1CYP1A2 | |
| SCHEMBL15430481 | 1.00 | DEGS1 (0.50) | DEGS1SLC6A2SLC6A4ALDH1A1CYP1A2 | |
| SCHEMBL1100407 | 1.00 | DEGS1 (0.50) | DEGS1SLC6A2SLC6A4ALDH1A1CYP1A2 | |
| SCHEMBL14097153 | 0.86 | ALDH1A1 (0.63) | SLC6A2SLC6A4ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16585071 | 0.84 | SLC6A3 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4718112 | 0.84 | SLC6A4 (0.55) | SLC6A2SLC6A4ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4678571 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A4ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16585396 | 0.84 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3970521 | 0.84 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2359242 | 0.84 | MAPT (0.56) | SLC6A2SLC6A4ALDH1A1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855419-B1 | NEW INDANYLOXYPHENYLCYCLOPROPANECARB OXYLIC ACIDS | BOEHRINGER INGELHEIM INT (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-1916234-B1 | CYCLOPROPANECARBOXYLIC ACID COMPOUND | TAKEDA PHARMACEUTICAL (JP) | 2014-11-12 | — | — | EP | disclosed |