Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15680112 | 0.82 | TSHR (0.49) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 | |
| SCHEMBL15680115 | 0.82 | CYP2C19 (0.33) | CYP2C9CYP2C19CYP1A2ABCB1CYP3A4 | |
| SCHEMBL23885407 | 0.80 | CYP1A2 (0.56) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 | |
| SCHEMBL30254696 | 0.80 | CYP1A2 (0.56) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 | |
| SCHEMBL23885028 | 0.79 | CYP1A2 (0.51) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 | |
| SCHEMBL30254957 | 0.79 | CYP1A2 (0.51) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 | |
| SCHEMBL15680113 | 0.78 | CYP1A2 (0.54) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 | |
| SCHEMBL15680117 | 0.78 | CYP2C9 (0.67) | CYP2C9CYP2C19CYP1A2PDK1PDK2 | |
| SCHEMBL4568238 | 0.77 | CYP1A2 (0.49) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 | |
| SCHEMBL4568236 | 0.77 | CYP1A2 (0.49) | CYP2C9CYP2C19CYP1A2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346743-B2 | Processes for the synthesis of 2-amino-4,6-dimethoxybenzamide and other benzamide compounds | ALBEMARLE CORPORATION (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346743-B2 | Processes for the synthesis of 2-amino-4,6-dimethoxybenzamide and other benzamide compounds | ALBEMARLE CORPORATION (US) | 2016-05-24 | — | — | US | disclosed |
| US-20160102046-A1 | PROCESSES FOR THE SYNTHESIS OF 2-AMINO-4,6-DIMETHOXYBENZAMIDE AND OTHER BENZAMIDE COMPOUNDS | ALBEMARLE CORPORATION (US) | 2016-04-14 | — | — | US | disclosed |
| US-20160102046-A1 | PROCESSES FOR THE SYNTHESIS OF 2-AMINO-4,6-DIMETHOXYBENZAMIDE AND OTHER BENZAMIDE COMPOUNDS | ALBEMARLE CORPORATION (US) | 2016-04-14 | — | — | US | disclosed |
| US-8884046-B2 | Compounds useful in the synthesis of benzamide compounds | RESVERLOGIX CORP. (CA) | 2014-11-11 | — | — | US | disclosed |
| US-8884046-B2 | Compounds useful in the synthesis of benzamide compounds | RESVERLOGIX CORP. (CA) | 2014-11-11 | — | — | US | disclosed |
| US-20140107369-A1 | COMPOUNDS USEFUL IN THE SYNTHESIS OF BENZAMIDE COMPOUNDS | RESVERLOGIX CORP. (CA) | 2014-04-17 | — | — | US | disclosed |
| US-20140107369-A1 | COMPOUNDS USEFUL IN THE SYNTHESIS OF BENZAMIDE COMPOUNDS | RESVERLOGIX CORP. (CA) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160102046-A1 | PROCESSES FOR THE SYNTHESIS OF 2-AMINO-4,6-DIMETHOXYBENZAMIDE AND OTHER BENZAMIDE COMPOUNDS | ALKBH3, ALKBH2, ALKBH1 | CYP2C9 865/4885CYP2C19 1080/4885CYP1A2 341/4885 |
| US-20140107369-A1 | COMPOUNDS USEFUL IN THE SYNTHESIS OF BENZAMIDE COMPOUNDS | DDC, AADAC, BRD4 | CYP2C9 1184/4885CYP2C19 968/4885CYP1A2 780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.