Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA6 | P23280 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA3 | P07451 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779433 | 0.87 | LTA4H (0.39) | LTA4HPAOXALDH1A1CA12CA7 | |
| SCHEMBL20389259 | 0.82 | CYP1A2 (0.45) | CYP1A2ALDH1A1LMNATDP1ALOX15 | |
| SCHEMBL17428464 | 0.81 | CYP1A2 (0.55) | CYP1A2PAOXALDH1A1MEN1RECQL | |
| SCHEMBL10837120 | 0.80 | CYP1A2 (0.64) | CYP1A2LTA4HPAOXALDH1A1CA12 | |
| SCHEMBL13616524 | 0.79 | DGKA (0.39) | LTA4HALDH1A1CA12CA7CA9 | |
| SCHEMBL13616523 | 0.79 | DGKA (0.39) | LTA4HALDH1A1CA12CA7CA9 | |
| SCHEMBL13756032 | 0.79 | CYP1A2 (0.62) | CYP1A2LTA4HALDH1A1CA12CA6 | |
| SCHEMBL11374530 | 0.79 | CYP1A2 (0.62) | CYP1A2LTA4HALDH1A1CA12CA6 | |
| Hydrochloric Acid SCHEMBL26095448 | 0.79 | CYP1A2 (0.62) | CYP1A2LTA4HPAOXALDH1A1KMT2A | |
| SCHEMBL13616503 | 0.79 | ALDH1A1 (0.35) | LTA4HALDH1A1KMT2ATHRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9403853-B2 | Trimethylolpropane core, phosphonic acid terminated dendrimer and its preparation method | TONGJI UNIVERSITY (CN) | 2016-08-02 | — | — | US | disclosed |
| US-20140332470-A1 | Trimethylolpropane core, phosphonic acid terminated dendrimer and its preparation method | TONGJI UNIVERSITY (CN) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140332470-A1 | Trimethylolpropane core, phosphonic acid terminated dendrimer and its preparation method | PHOSPHO1, CACNA1H, KCNN2 | CYP1A2 4007/4885LTA4H 1769/4885PAOX 296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.