Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.56 |
| ▸ | PARP1 | P09874 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 4/20 | 0.53 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.48 |
| ▸ | PARG | Q86W56 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31283720 | 0.86 | HSD17B10 (0.57) | KDM4EHSD17B10LMNATNKS2PARP1 | |
| SCHEMBL19104138 | 0.83 | TNKS (0.52) | KDM4EHSD17B10LMNATNKS2PARP1 | |
| SCHEMBL21467158 | 0.80 | PKM (0.59) | KDM4EHSD17B10LMNATNKS2PARP1 | |
| SCHEMBL22101663 | 0.80 | TNKS2 (0.59) | LMNATNKS2PARP1NPC1ALDH1A1 | |
| SCHEMBL8198982 | 0.80 | TNKS (0.50) | HSD17B10TNKS2PARP1ALDH1A1POLB | |
| SCHEMBL7263029 | 0.80 | KDM4E (0.66) | KDM4EHSD17B10LMNATNKS2PARP1 | |
| SCHEMBL29535139 | 0.80 | KDM4E (0.66) | KDM4EHSD17B10LMNATNKS2PARP1 | |
| SCHEMBL13618942 | 0.77 | KDM4E (0.59) | KDM4EHSD17B10LMNATNKS2PARP1 | |
| SCHEMBL5313776 | 0.77 | TYMS (0.72) | KDM4EHSD17B10LMNATNKS2PARP1 | |
| SCHEMBL3115005 | 0.77 | TYMS (0.72) | KDM4EHSD17B10LMNATNKS2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9700543-B2 | GLP-1 receptor stabilizers and modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2017-07-11 | — | — | US | disclosed |
| US-20160310471-A1 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | RECEPTOS LLC | 2016-10-27 | — | — | US | disclosed |
| US-9278910-B2 | GLP-1 receptor stabilizers and modulators | RECEPTOS, INC. (US) | 2016-03-08 | — | — | US | disclosed |
| US-20140336185-A1 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | RECEPTOS LLC | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336185-A1 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | GLP1R, GIPR, GHSR | KDM4E 3905/4885HSD17B10 4277/4885LMNA 3533/4885 |
| US-20160310471-A1 | NOVEL GLP-1 RECEPTOR STABILIZERS AND MODULATORS | GLP1R, GIPR, GHSR | KDM4E 3905/4885HSD17B10 4277/4885LMNA 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.