SCHEMBL16232789

SCHEMBL16232789

CC(=O)NC1C(O)[C@H](O[C@@H]2OC(CO[C@]3(OC=O)C[C@@H](O)[C@@H](C)C([C@H](O)C(O)CO)O3)[C@H](O)[C@H](O)C2O)[C@H](CO)O[C@H]1OC1[C@@H](OCC2O[C@@H](O[C@@H]3C(CO)O[C@@H](O[C@@H]4C(CO)O[C@@H](C)C(NC(C)=O)[C@H]4O)C(NC(C)=O)[C@H]3O)C(O)[C@@H](O[C@H]3OC(CO)[C@@H](O)C(O)C3O[C@@H]3OC(CO)[C@@H](O[C@@H]4OC(CO)[C@H](O)[C@H](O)C4O)[C@H](O)C3NC(C)=O)[C@@H]2O)OC(CO)[C@@H](O)[C@@H]1O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SELE P16581 4/20 0.46
▸ SIGLEC7 Q9Y286 6/20 0.46
▸ MAG P20916 6/20 0.46
▸ SELL P14151 2/20 0.41
▸ SELP P16109 1/20 0.41
▸ CD209 Q9NNX6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16232743 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL17195743 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL16187860 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL18926409 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL16312025 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL18926408 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL12197018 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL16232760 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL16312003 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP
SCHEMBL17195764 1.00 SELE (0.46) SELESIGLEC7MAGSELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9802996-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2017-10-31 — — US disclosed
US-9708413-B2 Glycosylated linker, compound containing glycosylated linker moiety and physiologically active substance moiety or salt thereof, and methods for producing said compound or salt thereof GLYTECH, INC. (JP) 2017-07-18 — — US disclosed
US-20160368961-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GLYTECH, INC. (JP) 2016-12-22 — — US disclosed
US-9422357-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2016-08-23 — — US disclosed
US-20150306235-A1 SUGAR CHAIN-ATTACHED LINKER, COMPOUND CONTAINING SUGAR CHAIN-ATTACHED LINKER AND PHYSIOLOGICALLY ACTIVE SUBSTANCE OR SALT THEREOF, AND METHOD FOR PRODUCING SAME GLYTECH INC (JP) 2015-10-29 — — US disclosed
US-20150299337-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID U OR SALT THEREOF GLYTECH INC (JP) 2015-10-22 — — US disclosed
US-20140336116-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GLYTECH, INC. (JP) 2014-11-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299337-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID U OR SALT THEREOF CD44, CSGALNACT1, UGGT1 SELE 148/4885SIGLEC7 8/4885MAG 644/4885
US-20140336116-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GIPR, SSTR4, SSTR5 SELE 430/4885SIGLEC7 104/4885MAG 778/4885
US-20150306235-A1 SUGAR CHAIN-ATTACHED LINKER, COMPOUND CONTAINING SUGAR CHAIN-ATTACHED LINKER AND PHYSIOLOGICALLY ACTIVE SUBSTANCE OR SALT THEREOF, AND METHOD FOR PRODUCING SAME SI, ENGASE, DNPEP SELE 219/4885SIGLEC7 29/4885MAG 1177/4885
US-20160368961-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GIPR, SSTR3, SSTR4 SELE 440/4885SIGLEC7 92/4885MAG 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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