Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.68 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.68 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 0.68 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 0.68 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 4/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16231608 | 0.83 | MAP3K11 (0.61) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL1395124 | 0.81 | TLK2 (1.00) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL29908697 | 0.81 | TLK2 (1.00) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL1395126 | 0.81 | TLK2 (1.00) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL2230665 | 0.81 | TLK2 (1.00) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL16231618 | 0.77 | MAP3K11 (0.60) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL16231615 | 0.77 | TLK2 (0.70) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL9886520 | 0.77 | MAP3K11 (0.64) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL16231617 | 0.77 | TLK2 (0.60) | MAP3K11TLK2NEK7NEK6MELK | |
| SCHEMBL16234131 | 0.76 | TLK2 (0.69) | MAP3K11TLK2NEK7NEK6MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336184-A1 | METHOD TO ENHANCE COGNITION | BAYLOR COLLEGE OF MEDICINE | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336184-A1 | METHOD TO ENHANCE COGNITION | EIF2AK2, EEF2K, EIF2AK1 | MAP3K11 621/4885TLK2 785/4885NEK7 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.