Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLK2 | Q86UE8 | 14/20 | 1.00 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 1.00 |
| ▸ | NEK7 | Q8TDX7 | 1/20 | 1.00 |
| ▸ | NEK6 | Q9HC98 | 1/20 | 1.00 |
| ▸ | MELK | Q14680 | 2/20 | 0.69 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | RET | P07949 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | CDK7 | P50613 | 2/20 | 0.47 |
| ▸ | CDK9 | P50750 | 2/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908697 | 1.00 | TLK2 (1.00) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL1395124 | 1.00 | TLK2 (1.00) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL1395126 | 1.00 | TLK2 (1.00) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL16231615 | 0.82 | TLK2 (0.70) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL23252181 | 0.81 | MELK (1.00) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL16234131 | 0.81 | TLK2 (0.69) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL16234132 | 0.81 | MAP3K11 (0.68) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL16234139 | 0.79 | TLK2 (0.65) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL16234143 | 0.78 | TLK2 (0.64) | TLK2MAP3K11NEK7NEK6MELK | |
| SCHEMBL9886520 | 0.78 | MAP3K11 (0.64) | TLK2MAP3K11NEK7NEK6MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4655070-A1 | METHODS OF HYPER- AND HYPO-METHYLATION ANALYSIS FOR DISEASE DETECTION | The Regents of the University of California (US) | 2025-12-03 | — | — | EP | claimed |
| US-20250092446-A1 | METHODS OF METHYLATION ANALYSIS FOR DISEASE DETECTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-03-20 | — | — | US | claimed |
| WO-2024159118-A1 | METHODS OF HYPER- AND HYPO-METHYLATION ANALYSIS FOR DISEASE DETECTION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-08-02 | — | — | WO | claimed |
| US-20240228552-A9 | NANOPORE TWEEZER APPROACH FOR PROTEIN KINASE ALLOSTERIC DRUG SCREENING | UNIVERSITY OF MASSACHUSETTS | 2024-07-11 | — | — | US | claimed |
| US-20240132551-A1 | NANOPORE TWEEZER APPROACH FOR PROTEIN KINASE ALLOSTERIC DRUG SCREENING | UNIV MASSACHUSETTS (US) | 2024-04-25 | — | — | US | claimed |
| CN-116850184-A | Application of inhibitor of targeted EIF2AK2 protein in preparation of medicines for preventing and/or treating pregnancy loss | 中山大学附属第八医院（深圳福田） | 2023-10-10 | — | — | CN | claimed |
| EP-4238292-A1 | ONE-WAY DELAY MEASUREMENT IN A PACKET-SWITCHED COMMUNICATION NETWORK | Telecom Italia S.p.A. (IT) | 2023-09-06 | — | — | EP | claimed |
| CN-116070247-B | Method for generating and performing electronic contracts in sequence | 杭州易签宝网络科技有限公司 | 2023-07-18 | — | — | CN | claimed |
| CN-116399167-A | Gun precision verification method | 中国人民解放军69243部队 | 2023-07-07 | — | — | CN | claimed |
| CN-116070247-A | Method for generating and performing electronic contracts in sequence | 杭州易签宝网络科技有限公司 | 2023-05-05 | — | — | CN | claimed |
| CN-113657322-B | Face recognition method and system based on public key ciphertext comparison | 广东君略科技咨询有限公司 | 2022-06-17 | — | — | CN | claimed |
| WO-2022090292-A1 | ONE-WAY DELAY MEASUREMENT IN A PACKET-SWITCHED COMMUNICATION NETWORK | TELECOM ITALIA S.P.A. (IT) | 2022-05-05 | — | — | WO | claimed |
| EP-4743587-A1 | METHODS FOR ASSAYING CIRCULATING TUMOR DNA | Natera, Inc. (US) | 2026-05-20 | — | — | EP | disclosed |
| US-20250392478-A1 | SYSTEM AND METHOD FOR SECURE LOCATION-PROOF & ANONYMOUS PRIVACY-PRESERVING SPECTRUM ACCESS | UNIV SOUTH FLORIDA (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4655070-A1 | METHODS OF HYPER- AND HYPO-METHYLATION ANALYSIS FOR DISEASE DETECTION | The Regents of the University of California (US) | 2025-12-03 | — | — | EP | disclosed |
| EP-4646493-A1 | METHODS AND COMPOSITIONS FOR AMPLIFYING METHYLATED TARGET DNA MOLECULES | Natera, Inc. (US) | 2025-11-12 | — | — | EP | disclosed |
| US-20150258061-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-17 | — | — | US | disclosed |
| US-8993615-B2 | Compositions and methods for treatment of neurodegenerative disease | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20110172206-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-07-14 | — | — | US | disclosed |
| WO-2010017541-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE | THE JOHNS HOPKINS UNIVERSITY (US) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150258061-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE | CLN6, PSEN2, CHAT | TLK2 3426/4885MAP3K11 3254/4885NEK7 1445/4885 |
| US-20250392478-A1 | SYSTEM AND METHOD FOR SECURE LOCATION-PROOF & ANONYMOUS PRIVACY-PRESERVING SPECTRUM ACCESS | SET, TES, TMPRSS2 | TLK2 1221/4885MAP3K11 3128/4885NEK7 746/4885 |
| US-20110172206-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF NEURODEGENERATIVE DISEASE | CLN6, PSEN2, CHAT | TLK2 3426/4885MAP3K11 3254/4885NEK7 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.