Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 5/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 2/20 | 0.51 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.51 |
| ▸ | PRKX | P51817 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.51 |
| ▸ | PKN2 | Q16513 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.51 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.51 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL247680 | 0.76 | EPHX1 (0.53) | CTRB1MMEMAPK1 | |
| SCHEMBL11487694 | 0.75 | CTRB1 (0.71) | CTRB1ROCK2PRKACAIRAK1PRKX | |
| SCHEMBL14959409 | 0.75 | MME (0.52) | MME | |
| SCHEMBL5685800 | 0.73 | CTRB1 (0.73) | CTRB1ROCK2PRKACAIRAK1PRKX | |
| SCHEMBL3682311 | 0.73 | CTRB1 (0.73) | CTRB1ROCK2PRKACAIRAK1PRKX | |
| SCHEMBL3682310 | 0.73 | CTRB1 (0.73) | CTRB1ROCK2PRKACAIRAK1PRKX | |
| SCHEMBL5262773 | 0.73 | CNR1 (0.72) | CNR1CNR2 | |
| SCHEMBL11582081 | 0.72 | ROCK2 (0.70) | CTRB1ROCK2PRKACAIRAK1PRKX | |
| SCHEMBL11582078 | 0.72 | ROCK2 (0.70) | CTRB1ROCK2PRKACAIRAK1PRKX | |
| SCHEMBL12029124 | 0.72 | CTRB1 (0.71) | CTRB1ROCK2PRKACAIRAK1PRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014184235-A1 | BENZAMIDE TRPA1 ANTAGONISTS | Acturum Life Science AB (SE) | 2014-11-20 | — | — | WO | claimed |
| WO-2014184235-A1 | BENZAMIDE TRPA1 ANTAGONISTS | Acturum Life Science AB (SE) | 2014-11-20 | — | — | WO | disclosed |