Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A9 | P06702 | 5/20 | 0.52 |
| ▸ | FABP4 | P15090 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235684 | 0.89 | S100A9 (0.40) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16235506 | 0.86 | S100A9 (0.39) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16235298 | 0.81 | FABP4 (0.41) | S100A9FABP4MEN1KMT2AACLY | |
| SCHEMBL16235650 | 0.80 | S100A9 (0.39) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16236114 | 0.74 | FABP4 (0.40) | FABP4MEN1KMT2AACLY | |
| SCHEMBL16235792 | 0.73 | CCR4 (0.49) | S100A9TP53ACLYCCR4 | |
| SCHEMBL16235401 | 0.72 | FABP4 (0.39) | FABP4MEN1KMT2AACLY | |
| SCHEMBL16235235 | 0.72 | TP53 (0.41) | MEN1KMT2ATP53ACLYALDH1A1 | |
| SCHEMBL16235729 | 0.72 | S100A9 (0.41) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16235390 | 0.70 | GAA (0.41) | S100A9TP53ACLYPKMCCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | claimed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | claimed |