Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A9 | P06702 | 4/20 | 0.40 |
| ▸ | FABP4 | P15090 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ACLY | P53396 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235506 | 0.93 | S100A9 (0.39) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16235464 | 0.89 | S100A9 (0.52) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16235235 | 0.83 | TP53 (0.41) | MEN1KMT2ATP53ACLYALDH1A1 | |
| SCHEMBL16236114 | 0.81 | FABP4 (0.40) | FABP4MEN1KMT2AACLYHSD11B1 | |
| SCHEMBL16235401 | 0.77 | FABP4 (0.39) | FABP4MEN1KMT2AACLYHSD11B1 | |
| SCHEMBL16235107 | 0.76 | TP53 (0.39) | MEN1KMT2ATP53ACLYALDH1A1 | |
| SCHEMBL16235298 | 0.74 | FABP4 (0.41) | S100A9FABP4MEN1KMT2AACLY | |
| SCHEMBL16235650 | 0.74 | S100A9 (0.39) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16235729 | 0.71 | S100A9 (0.41) | S100A9FABP4MEN1KMT2ATP53 | |
| SCHEMBL16235545 | 0.70 | HSD11B1 (0.46) | MEN1KMT2ATP53ALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | claimed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | claimed |