SCHEMBL16236012

SCHEMBL16236012

CCOC(=O)OC(C)CC(C)SC(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
SOAT1 P35610 1/20 0.38
LMNA P02545 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16235990 0.83 ALDH1A1 (0.40) ALDH1A1SOAT1LMNAHSD17B10
SCHEMBL10344105 0.81 ALDH1A1 (0.55) ALDH1A1SOAT1LMNAHSD17B10
SCHEMBL16236170 0.81 MEN1 (0.34)
SCHEMBL16236444 0.81 ALDH1A1 (0.35) ALDH1A1SOAT1
SCHEMBL16235946 0.76 LMNA (0.43) ALDH1A1LMNA
SCHEMBL16235696 0.76 KMT2A (0.41) ALDH1A1LMNA
SCHEMBL18050569 0.74 ALDH1A1 (0.46) ALDH1A1SOAT1LMNAHSD17B10
SCHEMBL2986945 0.73 ALDH1A1 (0.55) ALDH1A1SOAT1LMNAHSD17B10
SCHEMBL2984393 0.73 ALDH1A1 (0.55) ALDH1A1SOAT1LMNAHSD17B10
SCHEMBL6890292 0.73 ALDH1A1 (0.55) ALDH1A1SOAT1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005860-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2018-06-26 US disclosed
EP-2997049-B1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA SRL (IT) 2017-08-23 EP disclosed
US-20170166667-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-06-15 US disclosed
US-9644051-B2 Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2017-05-09 US disclosed
US-20160090428-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia, s.r.l. (IT) 2016-03-31 US disclosed
EP-2997049-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS Basell Poliolefine Italia S.r.l. (IT) 2016-03-23 EP disclosed
WO-2014184289-A1 CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2014-11-20 WO disclosed
EP-2803679-A1 Catalyst components for the polymerization of olefins Basell Poliolefine Italia S.r.l. (IT) 2014-11-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10005860-B2 Catalyst components for the polymerization of olefins OXER1, OXSR1, NR0B2 ALDH1A1 2092/4885SOAT1 75/4885LMNA 4419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.