Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.82 |
| ▸ | TSHR | P16473 | 4/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.42 |
| ▸ | ADH1C | P00326 | 1/20 | 0.42 |
| ▸ | ADH1A | P07327 | 1/20 | 0.42 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | ADH7 | P40394 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768463 | 1.00 | ALDH1A1 (0.82) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL16237152 | 0.98 | ALDH1A1 (0.86) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL11096395 | 0.96 | ALDH1A1 (0.83) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL965573 | 0.90 | TSHR (0.65) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL14365914 | 0.90 | TSHR (1.00) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL23611735 | 0.90 | TSHR (1.00) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL965893 | 0.90 | TSHR (0.65) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL123557 | 0.90 | TSHR (1.00) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL965056 | 0.90 | TSHR (0.65) | ALDH1A1TSHRCYP3A4LMNAKDM4E | |
| SCHEMBL16237335 | 0.89 | TSHR (0.79) | ALDH1A1TSHRCYP3A4LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331659-A1 | N,N-DIHYDROCARBONYL AMINO CARBOXYLIC ACID, PREPARATION METHOD THEREFOR AND USE THEREOF | Fujian Golden Dragon Rare-Earth Co., Ltd. (CN) | 2023-10-19 | — | — | US | disclosed |
| US-20160096819-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2016-04-07 | — | — | US | disclosed |
| EP-2997020-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2016-03-23 | — | — | EP | disclosed |
| CN-105189477-A | Process for preparing n-substituted 1h-pyrazole-5-carboxylic acid compounds and derivatives thereof | BASF SE | 2015-12-23 | — | — | CN | disclosed |
| WO-2014184343-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | BASF SE (DE) | 2014-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331659-A1 | N,N-DIHYDROCARBONYL AMINO CARBOXYLIC ACID, PREPARATION METHOD THEREFOR AND USE THEREOF | SLC7A1, SLC38A7, ASNS | ALDH1A1 1644/4885TSHR 3219/4885CYP3A4 3718/4885 |
| US-20160096819-A1 | PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLIC ACID COMPOUNDS AND DERIVATIVES THEREOF | CA3, CA2, CA1 | ALDH1A1 989/4885TSHR 959/4885CYP3A4 250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.