Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2826202 | 0.90 | BRD4 (0.47) | UCHL1MEN1KMT2APKMCA12 | |
| SCHEMBL14746472 | 0.89 | CA12 (0.49) | UCHL1MEN1KMT2ACA12CA1 | |
| SCHEMBL16861683 | 0.86 | ALDH1A1 (0.42) | UCHL1MEN1KMT2APKMCA12 | |
| SCHEMBL2825580 | 0.86 | UCHL1 (0.40) | UCHL1CA12CA1CA2CA7 | |
| SCHEMBL2823123 | 0.85 | BRD4 (0.41) | UCHL1MEN1KMT2ACA12CA1 | |
| SCHEMBL20377196 | 0.84 | CA12 (0.59) | UCHL1MEN1KMT2ACA12CA1 | |
| SCHEMBL16559890 | 0.84 | CA12 (0.44) | UCHL1MEN1KMT2ACA12CA1 | |
| SCHEMBL1857506 | 0.84 | CA12 (0.44) | UCHL1MEN1KMT2ACA12CA1 | |
| SCHEMBL2822082 | 0.82 | ALDH1A1 (0.42) | UCHL1MEN1KMT2ACA12CA1 | |
| SCHEMBL2821676 | 0.82 | BRD4 (0.39) | UCHL1MEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014186704-A2 | NOVEL COMPOUNDS FOR THE TREATMENT OF CYSTIC FIBROSIS | N30 PHARMACEUTICALS, INC. (US) | 2014-11-20 | — | — | WO | disclosed |