SCHEMBL16239123

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29908819	0.81	PRMT1 (0.52)	NCEH1HSP90AA1CRHBPCRHR2TSHR
	SCHEMBL15090932	0.81	PRMT1 (0.52)	NCEH1HSP90AA1CRHBPCRHR2TSHR
	SCHEMBL16239229	0.78	NAMPT (0.46)	NCEH1HSP90AA1CRHBPCRHR2TSHR
	SCHEMBL15091138	0.77	KAT6A (0.45)	NCEH1HSP90AA1CRHBPCRHR2TSHR
	SCHEMBL16239122	0.76	ANO1 (0.46)	NCEH1HSP90AA1CRHBPCRHR2ANO1
	SCHEMBL12047547	0.73	TSHR (0.54)	NCEH1HSP90AA1CRHBPCRHR2TSHR
	SCHEMBL16238945	0.73	HSP90AA1 (0.49)	NCEH1HSP90AA1CRHBPCRHR2TSHR
	SCHEMBL15091107	0.72	PRMT1 (0.41)	NCEH1HSP90AA1CRHBPCRHR2KMT2A
	SCHEMBL5285266	0.72	ALDH1A1 (0.45)	CRHBPCRHR2TSHRKMT2AMEN1
	SCHEMBL18010786	0.71	HSP90AA1 (0.49)	NCEH1HSP90AA1CRHBPCRHR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.