SCHEMBL16239229

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15090932	0.87	PRMT1 (0.52)	BRD4NCEH1TSHRHSP90AA1CRHBP
	SCHEMBL29908819	0.87	PRMT1 (0.52)	BRD4NCEH1TSHRHSP90AA1CRHBP
	SCHEMBL29908796	0.83	NAMPT (0.49)	NAMPTBRD4NCEH1KDM4AHDAC1
	SCHEMBL16239183	0.83	NAMPT (0.49)	NAMPTBRD4NCEH1KDM4AHDAC1
	SCHEMBL31455874	0.82	MAPK1 (0.52)	NAMPTBRD4HDAC1L3MBTL1MAPT
	SCHEMBL29908861	0.81	BCHE (0.46)	BRD4NCEH1TSHRKDM4AHSP90AA1
	SCHEMBL15091138	0.80	KAT6A (0.45)	BRD4NCEH1TSHRHSP90AA1CRHBP
	SCHEMBL16239122	0.79	ANO1 (0.46)	NCEH1HSP90AA1CRHBPCRHR2PRMT1
	SCHEMBL16239123	0.78	NCEH1 (0.45)	NCEH1TSHRHSP90AA1CRHBPCRHR2
	SCHEMBL15091107	0.76	PRMT1 (0.41)	BRD4NCEH1HSP90AA1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.