SCHEMBL16239183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29908796	1.00	NAMPT (0.49)	NAMPTBRD4HDAC1KDM4ANQO2
	SCHEMBL29908838	0.86	BRD4 (0.43)	NAMPTBRD4NCEH1GAA
	SCHEMBL15091057	0.86	BRD4 (0.43)	NAMPTBRD4NCEH1GAA
	SCHEMBL16239229	0.83	NAMPT (0.46)	NAMPTBRD4HDAC1KDM4ANQO2
	SCHEMBL16238914	0.82	TSHR (0.47)	NCEH1CYP1A2CYP2D6
	SCHEMBL29908813	0.79	BCHE (0.49)	BRD4KDM4ANQO2CA1CA2
	SCHEMBL15090993	0.79	BRD4 (0.46)	BRD4HDAC1MAPTHDAC10HDAC6
	SCHEMBL29908816	0.78	KMT2A (0.43)	GAA
	SCHEMBL16239142	0.78	KMT2A (0.43)	GAA
	SCHEMBL2807761	0.75	NAMPT (0.51)	NAMPTBRD4HDAC1KDM4AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.