Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19130750 | 0.95 | CYP19A1 (0.59) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL7759797 | 0.83 | CYP19A1 (0.39) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL2010436 | 0.82 | LMNA (0.59) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL19130960 | 0.81 | CYP19A1 (0.47) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL3788237 | 0.81 | CYP19A1 (0.55) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL3786185 | 0.80 | BACE1 (0.57) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL363290 | 0.79 | CYP3A4 (0.63) | CYP19A1LMNACYP3A4MEN1TP53 | |
| SCHEMBL3788510 | 0.78 | LMNA (0.48) | CYP19A1LMNAMAPTCYP3A4BACE1 | |
| SCHEMBL593772 | 0.78 | LMNA (0.63) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL1552646 | 0.78 | CYP19A1 (0.43) | CYP19A1LMNAMAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378645-A1 | LIQUID CRYSTAL ALIGNING AGENT | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
| EP-2803672-A1 | LIQUID CRYSTAL ALIGNING AGENT | Wako Pure Chemical Industries, Ltd. (JP) | 2014-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378645-A1 | LIQUID CRYSTAL ALIGNING AGENT | CYP17A1, AUP1, NR5A1 | CYP19A1 32/4885LMNA 33/4885MAPT 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.