Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19125163 | 0.91 | ALDH1A1 (0.44) | CYP19A1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19130750 | 0.85 | CYP19A1 (0.59) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL17737693 | 0.83 | ELANE (0.43) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL16239204 | 0.81 | CYP19A1 (0.55) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL19036064 | 0.80 | LMNA (0.38) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL17742662 | 0.77 | ELANE (0.42) | LMNAMAPTKDM4ECYP3A4MEN1 | |
| SCHEMBL17265774 | 0.76 | MEN1 (0.39) | LMNAMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL2010436 | 0.74 | LMNA (0.59) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL15497041 | 0.71 | MAPT (0.63) | CYP19A1LMNAMAPTKDM4ECYP3A4 | |
| SCHEMBL1552646 | 0.71 | CYP19A1 (0.43) | CYP19A1LMNAMAPTKDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9943810-B2 | Composite polyamide membrane post-treated with nitrous acid | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170203259-A1 | COMPOSITE POLYAMIDE MEMBRANE POST-TREATED WITH NITROUS ACID | THE DOW CHEMICAL COMPANY | 2017-07-20 | — | — | US | disclosed |