SCHEMBL16239689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16238956	0.84	HTT (0.44)	MAPK13MAPK12MAPK11MAPK14SIRT2
	SCHEMBL11901463	0.83	MAPT (0.55)	MAPK13MAPK12MAPK11MAPK14NPC1
	SCHEMBL28392058	0.82	BRD4 (0.45)	MAPK13MAPK12MAPK11MAPK14
	SCHEMBL16239629	0.81	MAPK13 (0.40)	MAPK13MAPK12MAPK11MAPK14SIRT2
	SCHEMBL1625533	0.75	TDP1 (0.42)	MAPK13MAPK12MAPK11MAPK14SIRT2
	SCHEMBL17947388	0.74	CD44 (0.43)	MAPK13MAPK12MAPK11MAPK14NPC1
	SCHEMBL16238935	0.74	MAPT (0.44)	MAPK14NPC1RAB9AKMT2AMAPT
	SCHEMBL1708324	0.73	CYP3A4 (0.65)	NPC1RAB9AMEN1KMT2AMAPT
	SCHEMBL14972592	0.73	METAP2 (0.40)	MAPK14NPC1RAB9AMEN1KMT2A
	Hydrochloric Acid SCHEMBL28755176	0.73	ALDH1A1 (0.63)	NPC1RAB9AMEN1KMT2ADDX3X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.