Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 11/20 | 0.59 |
| ▸ | AGTR2 | P50052 | 11/20 | 0.59 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.59 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94332 | 0.90 | AGTR1 (0.74) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL16376917 | 0.89 | AGTR2 (0.61) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL13757963 | 0.89 | AGTR2 (0.58) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL29699164 | 0.84 | AGTR1 (0.79) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL102109 | 0.82 | AGTR2 (0.62) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL6857540 | 0.81 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL787257 | 0.80 | AGTR2 (0.78) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL15132373 | 0.79 | AGTR2 (0.66) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL8468601 | 0.79 | AGTR2 (0.77) | AGTR1AGTR2ABCC3ABCC4ABCB11 | |
| SCHEMBL1653541 | 0.79 | AGTR2 (0.72) | AGTR1AGTR2ABCC3ABCC4ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933241-B2 | Method for producing olmesartan medoxomil | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-01-13 | — | — | US | disclosed |
| EP-2426126-B1 | METHOD FOR PRODUCING OLMESARTAN MEDOXOMIL | DAIICHI SANKYO CO LTD (JP) | 2014-11-19 | — | — | EP | disclosed |