SCHEMBL29699164

SCHEMBL29699164

C=C(C)c1nc(CCC)n(Cc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c1C(=O)OCc1oc(=O)oc1C

nearest known ligand 0.79

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 14/20 0.79
AGTR2 P50052 13/20 0.79
ABCC3 O15438 1/20 0.79
ABCC4 O15439 1/20 0.79
ABCB11 O95342 1/20 0.79
CYP3A4 P08684 1/20 0.79
PDE4D Q08499 1/20 0.79
PDE3A Q14432 1/20 0.79
SLCO1B3 Q9NPD5 1/20 0.79
TDP1 Q9NUW8 1/20 0.79
SLCO1B1 Q9Y6L6 1/20 0.79

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Olmesartan Medoxomil SCHEMBL29087653 0.88 AGTR1 (1.00) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL16403 0.88 AGTR1 (1.00) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28341316 0.88 AGTR1 (1.00) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL102109 0.88 AGTR2 (0.62) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL27822335 0.88 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL27934840 0.88 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL4132257 0.88 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28754180 0.88 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
Olmesartan Medoxomil SCHEMBL28547990 0.88 AGTR1 (0.99) AGTR1AGTR2ABCC3ABCC4ABCB11
SCHEMBL16376917 0.88 AGTR2 (0.61) AGTR1AGTR2ABCC3ABCC4ABCB11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117705962-A Related substance analysis method of olmesartan medoxomil amlodipine tablet 南京联智医药科技有限公司 2024-03-15 CN claimed
CN-114609289-B Method for detecting impurities in olmesartan medoxomil amlodipine compound preparation 云南龙津康佑生物医药有限公司 2023-11-14 CN claimed
CN-114609289-A Method for detecting impurities in olmesartan medoxomil and amlodipine compound preparation 云南龙津康佑生物医药有限公司 2022-06-10 CN claimed
CN-117705962-A Related substance analysis method of olmesartan medoxomil amlodipine tablet 南京联智医药科技有限公司 2024-03-15 CN disclosed
CN-114609289-B Method for detecting impurities in olmesartan medoxomil amlodipine compound preparation 云南龙津康佑生物医药有限公司 2023-11-14 CN disclosed
CN-114609289-A Method for detecting impurities in olmesartan medoxomil and amlodipine compound preparation 云南龙津康佑生物医药有限公司 2022-06-10 CN disclosed