Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.65 |
| ▸ | ACHE | P22303 | 8/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602960 | 0.93 | — | — | |
| SCHEMBL7252127 | 0.90 | EPHX1 (0.77) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL717081 | 0.87 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL14252129 | 0.87 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7788937 | 0.87 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7788927 | 0.87 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7788569 | 0.87 | EPHX1 (0.82) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL14433357 | 0.85 | EPHX1 (0.70) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL23735538 | 0.83 | EPHX1 (0.68) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL499170 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2808324-A1 | PYRROLE COMPOUND | Kabushiki Kaisha Yakult Honsha (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140343017-A1 | PYRROLE COMPOUND | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343017-A1 | PYRROLE COMPOUND | TUBB3, TUBB1, TUBB | EPHX1 4784/4885ACHE 4458/4885TDP1 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.